Both treatment groups in the HaLF DOME trial had similar demographics and baseline characteristics. Including ocular medical history of meibomian glad dysfunction (19.7%), blepharitis (8.3%), LASIK (16.6%) and Cataract surgery (15.9%). Patients presented with moderate-severe DED, as reflected in mean anaesthesised Schirmer scores of 5.39mm for LF (Lacrifill), and 5.47 mm for FF (Form Fit). Mean baseline OSDI was 48.8 for LF, and 46.4 for FF.²